Disorders and Treatments Guide: Depression

By Maria Colenso
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Depression is more than just feeling sad or having the blues. Major depression is a mood disorder characterized by a feeling of sadness or apathy so great that it influences a person's daily life and lasts for at least two or more consecutive weeks. It's a serious yet common mental illness that affects an estimated 15 million Americans annually -- and while it may happen only once in a lifetime, it's more commonly a recurrent pattern.

Signs & Symptoms

Depression manifests itself differently from person to person but common depressive symptoms include:

  • Feelings of sadness, guilt and worthlessness
  • Fatigue or loss of energy
  • Inability to concentrate
  • Changes in appetite, sleep and sex drive
  • Unexplained crying
  • Unexplained physical aches and pains
  • Irritability, restlessness, pessimism, anxiety
  • Loss of interest in normal day-to-day activities
  • Recurrent thoughts of death, dying and suicide


For more information, visit Mental Health America's factsheet about depression:
http://www.mentalhealthamerica.net/go/depression

Therapies

The onset of a major depressive episode is believed to be a combination of genetics and environment, and treatment plans may include antidepressants, psychotherapy or a combination of the two. According to the National Institute of Mental Health, more than 80 percent of people suffering from clinical depression show improvement with treatment.

Antidepressants such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclics (TCAs) and monoamine oxidase inhibitors (MAOIs) are all effective options.

Psychotherapy, specifically cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT), along with antidepressants may be the most effective method of treating major depression. Treatment plans should be tailored to the individual. For example, mild to moderate depression may be treated with psychotherapy alone while electroconvulsive therapy (ECT, or "shock" therapy) may help to relieve severe depression that is unresponsive to medications and psychotherapy.

Resources

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