See what's coming up on Transplant!:

Transplant! - Episode 1
D.J. DiVincenzo is 6 months old and has been hospitalized most of his short life. D.J. was born with "half a heart," a condition that forces the right side of his heart to carry the whole load. His parents, Dave and Jennifer, are at the hospital every day to be with their only child. After two surgeries, D.J.'s doctors agree that a transplant is the only option. The future appears bleak. But on Christmas Eve, a call comes in that a heart is available. The heart retrieval team rushes into action, flying to a hospital in upstate New York to bring back an infant heart. Through the early hours of the morning, surgeon Jonathan Chen carefully removes D.J.'s failing heart, and replaces it with a strong new one. With tears of joy, Jennifer realizes this surgery is the ultimate Christmas gift. But now a new and agonizing wait begins: to see if Will D.J.'s tiny body will accept or reject his new heart?

Linda Flanagan is 59. Her husband of 40 years watches helplessly as Linda struggles each day to find the energy to survive. Linda had a devastating heart attack six years ago, and was declared dead for almost an hour. Today, her heart is functioning, but at only 20 percent capacity. She's been called in twice for a potential transplant, but each time the heart went to someone else. With over a year and a half on the list, Linda's antibody levels are so high that she would most likely reject every heart available. Her cardiologist tells her that she must be hospitalized to undergo a plasmapheresis treatment to suppress her immune system—and hopefully, transform her into a possible recipient again. Cameras follow her through the medical treatments—and the waiting. Will Linda get her heart in time?

Transplant! - Episode 2
Rosario Mallare was an engaging, talkative salesman for British Airways until his weakened heart left him fighting for his life. Doctors implanted a pump called a Left Ventricular Assist Device that will keep the 58-year-old alive while a donor heart is sought. When we meet him, he is barely out of surgery, and extremely weak. Over the next eight weeks, however, Rosario gradually regains his health and vigor. Now, he is healthy enough to be placed on the transplant list, and is eligible to receive a heart.

Down the hall from Rosario is Kenneth Reng, 48, husband and father of an 8-year-old son. This friendly, successful car dealer was recently rushed to the hospital with his blood pressure crashing. He is now so weak that doctors believe Ken will die within weeks without a transplant. Luckily, a heart is located in South Carolina. In a breathtaking race against time, a team of doctors makes the long trip to recover the donor heart, as surgeons back at New York Presbyterian remove Ken's diseased one.

Hospitalized at the same time, Ken and Rosario, both strong-willed and positive men, push themselves to recover. They are released on the same day—Ken with a new human heart, Rosario with a titanium pump. The prognosis for both is excellent, but within five days, one of the two organs will tragically fail.