Stimulants — Cocaine/Crack/Methamphetamines
• Extremely dilated pupils
• Dry mouth and nose
• Bad breath
• Frequent lip licking and jaw moving
• Excessive activity, difficulty sitting still
• Lack of interest in food or sleep
• Irritable, argumentative and nervous
• Talkative, but conversation often lacks continuity, rapidly changes subjects
• Runny nose, cold or chronic sinus/nasal problems, nose bleeds
• Use or possession of paraphernalia, such as small spoons, razor blades, mirror, little bottles of white powder and plastic, glass or metal straws

Depressants
• Lack of facial expression or animation
• A flat or flaccid appearance
• Slurred speech

Note: There are few readily apparent symptoms. Abuse may be indicated by activities such as frequent visits to different physicians for prescriptions to treat "nervousness," "anxiety," or "stress," etc.

Narcotics/Prescription Drugs/Opium/Heroin/Codeine/Oxycontin
• Lethargic, drowsiness
• Constricted pupils that fail to respond to light
• Redness and raw nostrils from inhaling heroin in power form
• Scars or tracks on inner arms or other parts of the body from needle injections
• Use or possession of paraphernalia, such as syringes or bent spoons, bottle caps, eyedroppers, rubber tubing, cotton and needles
• Slurred speech

Note: While there may be no readily apparent symptoms of analgesic abuse, it may be indicated by frequent visits to different physicians or dentists for prescriptions to treat pain of non-specific origin. In cases where a patient has chronic pain and abuse of medication is suspected, it may be indicated by the amount of medication and frequency it's taken.

Inhalants — Solvents/Glue/Petrol/Aerosols
• Substance odor on breath and clothes
• Runny nose
• Watering eyes
• Slurred speech
• Impaired coordination
• Nausea, vomiting and diarrhea
• Slowed breathing
• Brain damage
• Poor muscle control
• Pain in the chest, muscles, and joints
• Heart trouble
• Severe depression and fatigue
• Loss of appetite
• Bronchial spasm
• Nosebleeds and sores on mouth
• Bizarre and reckless behavior
• Drowsiness or unconsciousness
• Suffocation and sudden death
• Presence of bags or rags containing dry plastic cement or other solvents at home, in locker at school or at work
• Discarded whipped cream cans, spray paint cans or similar chargers (containing nitrous oxide)
• Small bottles labeled "incense" (containing butyl nitrite)